To be effective, a drug must be efficiently delivered in sufficient quantities over a period of time long enough for it to carry out its desired effect. A major challenge in this sense is poor retention and bioavailability ...

Effective desymmetrization in copper-catalyzed intramolecular C–H insertion reactions of α-diazo-β-oxosulfones in the formation of fused thiopyran dioxides is described for the first time. The use of a copper–bis(oxazoline)–NaBARF ...

Artificial neural network (ANN) modelling is applied to predict the mean residence time of pharmaceutical formulation in a twin-screw granulator. Process parameters including feed flow rate, screw speed, and liquid to solid ...

The purpose of this study was to develop a resorbable, mouldable bone filler that can be used to repair damaged bone. Work was focused on the use of the resorbable polymer poly DL lactide (PDLLA). The ideal formulation ...

Organic wastewater pollution arising from industry is a growing concern. Industries are increasingly faced with more restrictive environmental regulation with regards to pollutant emissions and an increased interest in ...

Hydrogen is increasingly used in a variety of applications and holds promise as a replacement for fossil fuels. Biomass derived formic acid represents an excellent renewable material for hydrogen storage. This thesis is ...

The last number of years has seen the development of a wide range of nanoscale materials exhibiting new or improved properties with considerable potential for electronic, energy, and sensing applications. One could argue ...

Well defined mediatorless bioelectrocatalytic reduction of oxygen with high current densities of 0.8 mA cm(-2) was obtained on nanoporous gold electrodes modified with Myrothecium verrucaria bilirubin oxidase. A stable ...

The crystal structure containing (+/-)-3-methyl-2-phenylbutyramide with salicylic acid is the first example of a kryptoracemate co-crystal. It exhibits the first temperature mediated reversible single-crystal to single-crystal ...

Two isostructural metal–organic materials, Tripp-1-M (Tripp = 2,4,6-tris(4-pyridyl)pyridine; M =Co, Ni), that exhibit binodal 3,6-connected pyr network topology have been prepared and characterized. Tripp-1-M are based ...