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Potential effects of curcumin in the treatment of COVID-19 infection

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dc.contributor.author Zahedipour, Fatemeh
dc.contributor.author Hosseini, Seyede Atefe
dc.contributor.author Sathyapalan, Thozhukat
dc.contributor.author Majeed, Muhammed
dc.contributor.author Jamialahmadi, Tannaz
dc.contributor.author Al-Rasadi, Khalid
dc.contributor.author Banach, Maciej
dc.contributor.author Sahebkar, Amirhossein
dc.date.accessioned 2021-08-20T08:03:46Z
dc.date.available 2021-08-20T08:03:46Z
dc.date.issued 2020
dc.identifier.uri http://hdl.handle.net/10344/10497
dc.description peer-reviewed en_US
dc.description.abstract Coronavirus disease 2019 (COVID-19) outbreak is an ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with considerable mortality worldwide. The main clinical manifestation of COVID-19 is the presence of respiratory symptoms, but some patients develop severe cardiovascular and renal complications. There is an urgency to understand the mechanism by which this virus causes complications so as to develop treatment options. Curcumin, a natural polyphenolic compound, could be a potential treatment option for patients with coronavirus disease. In this study, we review some of the potential effects of curcumin such as inhibiting the entry of virus to the cell, inhibiting encapsulation of the virus and viral protease, as well as modulating various cellular signaling pathways. This review provides a basis for further research and development of clinical applications of curcumin for the treatment of newly emerged SARS-CoV-2. en_US
dc.language.iso eng en_US
dc.publisher Wiley and Sons Ltd en_US
dc.relation.ispartofseries Phytotherapy Research;34 (11), pp. 2911-2920
dc.relation.uri https://doi.org/10.1002/ptr.6738
dc.rights This is the peer reviewed author version of the following article: Potential effects of curcumin in the treatment of COVID-19 infection, Phytotherapy Research. 2020; 34: 2911– 2920 , which has been published in final form at https://doi.org/10.1002/ptr.6738 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. http://olabout.wiley.com/WileyCDA/Section/id-828039.html#terms en_US
dc.subject curcuminoids en_US
dc.subject viral infection en_US
dc.subject pulmonary fibrosis
dc.subject acute respiratory distress syndrome
dc.title Potential effects of curcumin in the treatment of COVID-19 infection en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1002/ptr.6738
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US


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