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Predictors of hospitalization in patients with rheumatic disease and COVID-19 in Ireland: data from the COVID-19 global rheumatology alliance registry

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dc.contributor.author Conway, Richard
dc.contributor.author Nikiphorou, Elena
dc.contributor.author Demetriou, Christiana A.
dc.contributor.author Low, Candice
dc.contributor.author Leamy, Kelly
dc.contributor.author Ryan, John G.
dc.contributor.author Kavanagh, Ronan
dc.contributor.author Fraser, Alexander D.
dc.contributor.author Carey, John J
dc.contributor.author O'Connell, Paul
dc.contributor.author Flood, Rachael M.
dc.contributor.author Mullan, Ronan H.
dc.contributor.author Kane, David J.
dc.contributor.author Robinson, Philip C.
dc.contributor.author Liew, Jean W.
dc.contributor.author Grainger, Rebecca
dc.contributor.author McCarthy, Geraldine
dc.date.accessioned 2021-07-22T11:56:21Z
dc.date.available 2021-07-22T11:56:21Z
dc.date.issued 2021
dc.identifier.uri http://hdl.handle.net/10344/10397
dc.description peer-reviewed en_US
dc.description.abstract Objectives Given the limited data regarding the risk of hospitalization in patients with rheumatic disease and coronavirus disease 2019 (COVID-19) in Ireland, we used the COVID-19 Global Rheumatology Alliance (GRA) registry data to study outcomes and their predictors. The primary objective was to explore potential predictors of hospitalization. Methods We examined data on patients and their disease-related characteristics entered in the COVID-19 GRA provider registry from Ireland (from 24 March 2020 to 31 August 2020). Multivariable logistic regression was used to assess the association of demographic and clinical characteristics with hospitalization. Results Of 105 patients, 47 (45.6%) were hospitalized and 10 (9.5%) died. Multivariable logistic regression analysis showed that age [odds ratio (OR) = 1.06, 95% CI 1.01, 1.10], number of co-morbidities (OR = 1.93, 95% CI 1.11, 3.35) and glucocorticoid use (OR = 15.01, 95% CI 1.77, 127.16) were significantly associated with hospitalization. A diagnosis of inflammatory arthritis was associated with lower odds of hospitalization (OR = 0.09, 95% CI 0.02, 0.32). Conclusion Increasing age, co-morbidity burden and glucocorticoid use were associated with hospitalization, whereas a diagnosis of inflammatory arthritis was associated with lower odds of hospitalization. en_US
dc.language.iso eng en_US
dc.publisher Oxford University Press en_US
dc.relation.ispartofseries Rheumatology Advances in Practice;
dc.subject rheumatic disease en_US
dc.subject COVID-19 en_US
dc.subject biologics en_US
dc.subject hospitalization en_US
dc.title Predictors of hospitalization in patients with rheumatic disease and COVID-19 in Ireland: data from the COVID-19 global rheumatology alliance registry en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1093/rap/rkab031
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US


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