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How do delirium motor subtypes differ in phenomenology and contributory aetiology? a cross-sectional, multisite study of liaison psychiatry and palliative care patients

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dc.contributor.author Glynn, Kevin
dc.contributor.author McKenna, Frank
dc.contributor.author Lally, Kevin
dc.contributor.author O'Donnell, Muireann
dc.contributor.author Grover, Sandeep
dc.contributor.author Chakrabarti, Subho
dc.contributor.author Avasthi, Ajit
dc.contributor.author Mattoo, Surendra K
dc.contributor.author Sharma, Akhilesh
dc.contributor.author Gosh, Abhishek
dc.contributor.author Shah, Ruchita
dc.contributor.author Hickey, David
dc.contributor.author Fitzgerald, James
dc.contributor.author Davis, Brid
dc.contributor.author O'Regan, Niamh
dc.contributor.author Adamis, Dimitrios
dc.contributor.author Williams, Olugbenja
dc.contributor.author Awan, Fahad
dc.contributor.author Dunne, Colm P.
dc.contributor.author Cullen, Walter
dc.contributor.author McInerney, Shane
dc.contributor.author McFarland, John
dc.contributor.author Jabbar, Faiza
dc.contributor.author O'Connell, Henry
dc.contributor.author Trzepacz, Paula T.
dc.contributor.author Leonard, Maeve
dc.contributor.author Meagher, David
dc.date.accessioned 2021-05-27T11:03:56Z
dc.date.available 2021-05-27T11:03:56Z
dc.date.issued 2021
dc.identifier.uri http://hdl.handle.net/10344/10116
dc.description peer-reviewed en_US
dc.description.abstract Objectives To investigate whether delirium motor subtypes differ in terms of phenomenology and contributory aetiology. Design Cross-sectional study. Setting International study incorporating data from Ireland and India across palliative care, old age liaison psychiatry and general adult liaison psychiatry settings. Participants 1757 patients diagnosed with delirium using criteria from the Diagnostic and Statistical Manual of Mental Disorders, Fourth edition (DSM IV). Primary and secondary outcome measures Hyperactive, mixed and hypoactive delirium subtypes were identified using the abbreviated version of the Delirium Motor Subtype Scale. Phenomenology was assessed using the Delirium Rating Scale Revised. Contributory aetiologies were assessed using the Delirium Aetiology Checklist (DEC), with a score >2 indicating that the aetiology was likely or definitely contributory. Results Hypoactive delirium was associated with dementia, cerebrovascular and systemic infection aetiologies (p<0.001) and had a lower overall burden of delirium symptoms than the other motor subtypes. Hyperactive delirium was associated with younger age, drug withdrawal and the DEC category other systemic aetiologies (p<0.001). Mixed delirium showed the greatest symptom burden and was more often associated with drug intoxication and metabolic disturbance (p<0.001). All three delirium motor subtypes had similar levels of impairment in attention and visuospatial functioning but differed significantly when compared with no subtype (p<0.001). Conclusions This study indicates a pattern of aetiology and symptomatology of delirium motor subtypes across a large international sample that had previously been lacking. It serves to improve our understanding of this complex condition and has implications in terms of early detection and management of delirium. en_US
dc.language.iso eng en_US
dc.publisher BMJ en_US
dc.relation.ispartofseries BMJ Open;11, e041214
dc.subject delirium en_US
dc.subject palliative care en_US
dc.subject aetiology en_US
dc.title How do delirium motor subtypes differ in phenomenology and contributory aetiology? a cross-sectional, multisite study of liaison psychiatry and palliative care patients en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1136/bmjopen-2020-04121
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US


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