University of Limerick Institutional Repository

How do delirium motor subtypes differ in phenomenology and contributory aetiology? a cross-sectional, multisite study of liaison psychiatry and palliative care patients

DSpace Repository

Show simple item record Glynn, Kevin McKenna, Frank Lally, Kevin O'Donnell, Muireann Grover, Sandeep Chakrabarti, Subho Avasthi, Ajit Mattoo, Surendra K Sharma, Akhilesh Gosh, Abhishek Shah, Ruchita Hickey, David Fitzgerald, James Davis, Brid O'Regan, Niamh A. Adamis, Dimitrios Williams, Olugbenga A. Awan, Fahad Dunne, Colum P. Cullen, Walter McInerney, Shane McFarland, John Jabbar, Faiza O'Connell, Henry Trzepacz, Paula T. Leonard, Maeve Meagher, David 2021-05-27T11:03:56Z 2021-05-27T11:03:56Z 2021
dc.description peer-reviewed en_US
dc.description.abstract Objectives To investigate whether delirium motor subtypes differ in terms of phenomenology and contributory aetiology. Design Cross-sectional study. Setting International study incorporating data from Ireland and India across palliative care, old age liaison psychiatry and general adult liaison psychiatry settings. Participants 1757 patients diagnosed with delirium using criteria from the Diagnostic and Statistical Manual of Mental Disorders, Fourth edition (DSM IV). Primary and secondary outcome measures Hyperactive, mixed and hypoactive delirium subtypes were identified using the abbreviated version of the Delirium Motor Subtype Scale. Phenomenology was assessed using the Delirium Rating Scale Revised. Contributory aetiologies were assessed using the Delirium Aetiology Checklist (DEC), with a score >2 indicating that the aetiology was likely or definitely contributory. Results Hypoactive delirium was associated with dementia, cerebrovascular and systemic infection aetiologies (p<0.001) and had a lower overall burden of delirium symptoms than the other motor subtypes. Hyperactive delirium was associated with younger age, drug withdrawal and the DEC category other systemic aetiologies (p<0.001). Mixed delirium showed the greatest symptom burden and was more often associated with drug intoxication and metabolic disturbance (p<0.001). All three delirium motor subtypes had similar levels of impairment in attention and visuospatial functioning but differed significantly when compared with no subtype (p<0.001). Conclusions This study indicates a pattern of aetiology and symptomatology of delirium motor subtypes across a large international sample that had previously been lacking. It serves to improve our understanding of this complex condition and has implications in terms of early detection and management of delirium. en_US
dc.language.iso eng en_US
dc.publisher BMJ en_US
dc.relation.ispartofseries BMJ Open;11, e041214
dc.subject delirium en_US
dc.subject palliative care en_US
dc.subject aetiology en_US
dc.title How do delirium motor subtypes differ in phenomenology and contributory aetiology? a cross-sectional, multisite study of liaison psychiatry and palliative care patients en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1136/bmjopen-2020-04121
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US
dc.internal.rssid 2999459

Files in this item

This item appears in the following Collection(s)

Show simple item record

Search ULIR


My Account