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Dietary fibre modulates the gut microbiota

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dc.contributor.author Cronin, Peter
dc.contributor.author Joyce, Susan A.
dc.contributor.author O'Toole, Paul W.
dc.contributor.author O'Connor, Eibhlís M.
dc.date.accessioned 2021-05-19T08:57:05Z
dc.date.available 2021-05-19T08:57:05Z
dc.date.issued 2021
dc.identifier.uri http://hdl.handle.net/10344/10092
dc.description peer-reviewed en_US
dc.description.abstract Dietary fibre has long been established as a nutritionally important, health-promoting food ingredient. Modern dietary practices have seen a significant reduction in fibre consumption compared with ancestral habits. This is related to the emergence of low-fibre “Western diets” associated with industrialised nations, and is linked to an increased prevalence of gut diseases such as inflammatory bowel disease, obesity, type II diabetes mellitus and metabolic syndrome. The characteristic metabolic parameters of these individuals include insulin resistance, high fasting and postprandial glucose, as well as high plasma cholesterol, low-density lipoprotein (LDL) and high-density lipoprotein (HDL). Gut microbial signatures are also altered significantly in these cohorts, suggesting a causative link between diet, microbes and disease. Dietary fibre consumption has been hypothesised to reverse these changes through microbial fermentation and the subsequent production of short-chain fatty acids (SCFA), which improves glucose and lipid parameters in individuals who harbour diseases associated with dysfunctional metabolism. This review article examines how different types of dietary fibre can differentially alter glucose and lipid metabolism through changes in gut microbiota composition and function. en_US
dc.language.iso eng en_US
dc.publisher MDPI en_US
dc.relation.ispartofseries Nutrients;13, 1655
dc.subject dietary fibre en_US
dc.subject metabolic health en_US
dc.title Dietary fibre modulates the gut microbiota en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.contributor.sponsor Department of Agriculture, Food and the Marine en_US
dc.relation.projectid 17F251 en_US
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US


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