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Now showing items 1844-1863 of 2465

Property prediction and residual stresses in aluminium alloy 7010

Flynn, Robert, Joseph (University of Limerick, 2013)

This project investigates the development of C-curves for aluminium alloy 7010 under various tempers and processing conditions and the subsequent use of quench factor analysis (OF A) for property prediction. Statistical ...
A proposed new architecture for embedded systems development based on IEC 61499 function blocks

O'Sullivan, Denis (University of Limerick, 2011)

Today’s automation and control networks are typically viewed as networks of devices and the necessary software developed piecemeal from each individual device’s perspective. The IEC 61499 standard defines a generic ...
Prospective assessment of systemic microRNAs as markers of response to neoadjuvant chemotherapy in breast cancer

McGuire, Andrew; Casey, Maire-Caitlin; Waldron, Ronan M.; Heneghan, Helen; Kalinina, Olga; Holian, Emma; McDermott, Ailbhe; Lowery, Aoife J.; Newell, John; Dwyer, Róisín M.; Miller, Nicola; Keane, Maccon; Brown, James A.L.; Kerin, Michael J. (MDPI, 2020)

Neoadjuvant chemotherapy (NACT) is used in locally advanced breast cancer to reduce tumour burden prior to surgical resection. However, only a subset of NACT treated patients will respond to treatment or achieve a pathologic ...
Prospects for the management of type 2 diabetes using food protein-derived peptides with dipeptidyl peptidase IV (DPP-IV) inhibitory activity

Nongonierma, Alice B.; Fitzgerald, Richard J. (Elsevier, 2016)

Since drug based inhibition of dipeptidyl peptidase IV (DPP-IV) is employed in type 2 (T2D) diabetes therapy, food protein hydrolysates which inhibit DPP- IV may also have potential in the management of T2D. Specific peptide ...
Protecting bactofencin A to enable its antimicrobial activity using mesoporous matrices

Durack, Edel; Mallen, Sarah; O'Connor, Paula M.; Rea, Mary C.; Ross, Paul R.; Hill, Colin; Hudson, Sarah P. (Elsevier, 2019)

There is huge global concern surrounding the emergence of antimicrobial resistant bacteria and this is resulting in an inability to treat infectious diseases. This is due to a lack of new antimicrobials coming to the market ...
Protein A-mediated binding of staphylococcus spp. to antibodies in flow cytometric assays and reduction of this binding by using Fc receptor blocking reagent

Cronin, Ultan P.; Girardeaux, Laura; O'Meara, Elaine; Wilkinson, Martin G. (American Society for Microbiology, 2020)

Staphylococcus aureus and other coagulase-positive Staphylococcus spp. bind the Fc region of IgG antibodies through expression of protein A (SpA). These species have consequently been a source of false-positive signals ...
Protein tyrosine phosphatase receptor-like genes are frequently hypermethylated in sporadic colorectal cancer

Laczmanska, Izabela; Karpinski, Pawel; Bebenek, Marek; Sedziak, Tomasz; Ramsey, David; Szmida, Elżbieta; Sasiadek, Maria Malgorzata (Nature Publishing Group, 2013)

Introduction: The activity of phosphatases could be influenced by genetic, as well as epigenetic alterations. In our study we have investigated the methylation status of four PTPRs: PTPRM, PTPRT, PTPRR and PTPRZ1, which ...
Proteolytic release of angiotensin converting enzyme inhibitory peptides from food proteins.

Norris, Roseanne (University of Limerick, 2013)

The potential of an Aspergillus niger derived prolyl endoproteinase (An-PEP) to produce potent angiotensin converting enzyme (ACE) inhibitory peptides was assessed. Bovine α- and β-casein were purified from acid caseinate ...
A prototype antifungal contact lens

Ciolino, Joseph B.; Hudson, Sarah P.; Mobbs, Ashley N.; Hoare, Todd R.; Iwata, Naomi G.; Fink, Gerald R.; Kohane, Daniel S. (Association for Research in Vision and Ophthalmology (ARVO), 2011)

PURPOSE. To design a contact lens to treat and prevent fungal ocular infections.METHODS. Curved contact lenses were created by encapsulating econazole-impregnated poly(lactic-co-glycolic) acid (PLGA) films in poly(hydroxyethyl ...
Prototype modelling of body surface maps using tangent distance

Patterson, Richard; MacKenzie, Gilbert (IWSM, 1999)

In recent years the tangent distance approach of Simard et al (1993) to pattern recognition tasks such as handwritten character recognition has proven successful. Simard's distance measure could be made locally invariant ...
Psychosocial factors in sustained attention work and contribution to work related musculoskeletal disorders

Wixted, Fiona (University of Limerick, 2017)

The world has entered what has become known as the fourth industrial revolution. Technological advancements in ICT and automation including IoT, cloud computing and smart robotics have changed industrial manufacturing ...
Psychosocial Interventions for Problem Alcohol Use in Primary Care Settings (PINTA): baseline feasibility data.

Klimas, Jan; Henihan, Anne Marie; McCombe, Geoff; Swan, Davina; Anderson, Rolande; Bury, Gerard; Dunne, Colum P.; Keenan, Eamon; Saunders, Jean; Williams Shorter, Gillian; Smyth, Bobby P.; Cullen, Walter (Taylor and Francis, 2015)

Objectives. Primary care is a key provider of long-term care for people who attend primary care for substance use treatment, especially those in methadone maintenance treatment. As many drink alcohol excessively, there is ...
Psychosocial risk exposures and musculoskeletal disorders across working-age males and females

Collins, John D.; O'Sullivan, Leonard (Wiley and Sons, 2010)

In 2008, The European Agency for Safety and Health at Work (EU-OSHA) reported that musculoskeletal disorders (MSDs) were the most common work-related health problem in Europe. Females are considered more susceptible to ...
Purification and characterization of a lysine-p-nitroanilide hydrolase, a broad specificity aminopeptidase, from the cytoplasm of Lactococcus lactis subsp. cremoris AM2

McDonnell, Maeve; Bouchier, Paul; Fitzgerald, Richard J.; O'Cuinn, Gerard (Cambridge University Press, 1999)

Summary. A hydrolase activity that cleaves lysyl-p-nitroanilide (Lys-pNA) has been purified from the cytoplasm of Lactococcus lactis subsp. cremoris AM2 by chromatography on DE52, DEAE Affi-Gel Blue Gel, Hydroxyapatite ...
A purpose-built model for the effective teaching of trigonometry: a transformationc of the van Hiele model

Walsh, Richard (University of Limerick, 2015)

There is widespread acknowledgement that students in second and third level education have diffculty with trigonometry. This is not only the case domestically in Ireland, but also internationally. Evidence exists ...
The purposeful adaptation of practice: an empirical study of distributed software development

Sigfridsson, Anders (University of Limerick, Department of Computer Science & Information Systems, 2010)

This thesis addresses the research question: how do software developers in distributed projects continually develop their practical knowledge through dealing with changing circumstances in daily work practice? The purpose ...
The pursuit of quality: a clinical directorate’s progress in clinical governance a case study of the women and children’s directorate, GUH (HSE)

de Burca, Stefán; Williams, Peter; Armstrong, Claire (Health Systems Research Centre, 2008)

The aim of the overall study is to inform the design and delivery of a high reliability clinical directorate. This report is the result of the mapping phase in the case study of the Women’s and Children’s Directorate, ...
Pursuit-evasion using evolutionary algorithms in an immnersive three-dimensional environment

Eaton, Malachy; Tuohy, Michael (IEEE Computer Society, 2002)

In view of the biological prevalence of pursuit-evasion conies6 they provide a useful test-bed for research into novel bio-inspired computing and control systems. In this paper we investigate the evolution of ...
Pyroelectricity in globular protein lysozyme films

Stapleton, Aimee; Noor, Mohamed R.; Haq, Ehtsham U.; Silien, Christophe; Soulimane, Tewfik; Tofail, Syed A.M. (AIP Publishing, 2018)

Pyroelectricity is the ability of certain non-centrosymmetric materials to generate an electric chargein response to a change in temperature and finds use in a range of applications from burglar alarms to thermal imaging. ...
Pyrolysis of biomass and biorefinery residual materials for production of advanced biofuels

Melligan, Fergus J. (University of Limerick, 2012)

The work carried out throughout this project has helped to further advance the area of biomass pyrolysis for the production of bio-oil. During the early stage of the project, the focus was on investigating the effect of ...

Now showing items 1844-1863 of 2465

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