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  • Carson, Brian P.; Del Bas, Josep Maria; Moreno-Navarrete, Jose Maria; Fernandez-Real, Jose Manuel; Mora, Silvia (Public Library of Science, 2013)
    Adiponectin is an adipokine secreted by white adipocytes involved in regulating insulin sensitivity in peripheral tissues. Secretion of adiponectin in adipocytes relies on the endosomal system, however, the intracellular ...
  • Day, John P.; Whiteley, Ellanor; Freeley, Michael; Long, Aideen; Malacrida, Beatrice; Kiely, Patrick A.; Baillie, George S. (Future Science, 2018)
    Aim: RACK1 is a multifunctional scaffolding protein that is expressed in many cellular compartments, orchestrating a number of signaling processes. RACK1 acts as a signaling hub to localize active enzymes to discrete ...
  • Guerin, Sarah; O'Donnell, Joseph; Haq, Ehtsham U.; McKeown, Cian; Silien, Christophe; Rhen, Fernando M.F.; Soulimane, Tewfik; Tofail, Syed A.M.; Thompson, Damien (American Physical Society, 2019)
    Single crystal L-amino acids can exhibit technologically useful piezoelectric and nonlinear optical properties. Here we predict, using density functional theory, the piezoelectric charge and strain and voltage tensors of ...
  • Ron, Dorit; Adams, David R.; Baillie, George S.; Long, Aideen; O'Connor, Rosemary; Kiely, Patrick A. (BioMed Central, 2013)
    This perspective summarises the first and long overdue RACK1 meeting held at the University of Limerick, Ireland, May 2013, in which RACK1's role in the immune system, the heart and the brain were discussed and its ...
  • Kiely, Maeve (University of Limerick, 2014)
    Breast cancer is a leading cause of cancer death worldwide but targeted therapies have proven to be very successful in the treatment of this disease. The aim of this study was to develop models and parameters that will ...
  • Kiely, Maeve; Adams, David R.; Hayes, Sheri L.; O'Connor, Rosemary; Baillie, George S.; Kiely, Patrick A. (Elsevier, 2017)
    Conflicting reports implicate the scaffolding protein RACK1 in the progression of breast cancer. RACK1 has been identified as a key regulator downstream of growth factor and adhesion signalling and as a direct binding ...
  • Adams, David R.; Ron, Dorit; Kiely, Patrick A. (BioMed Central, 2011)
    The Receptor for Activated C Kinase 1 (RACK1) is a member of the tryptophan-aspartate repeat (WD-repeat) family of proteins and shares significant homology to the β subunit of G-proteins (Gβ). RACK1 adopts a seven-bladed ...
  • Arshak, Khalil; Korostynska, Olga; Arshak, Arousian; Morris, Deirdre (IEEE Computer Society, 2005)
    The electrical properties of screen-printed TiO2 based thick films were explored in terms of gamma radiation influence. Screen-printed pn-heterojunctions and resistors were exposed to γ- radiation from a 137Cs source ...
  • Walsh, Gráinne (Springer, 2020)
    Radical constructivism was defined by von Glasersfeld as a theory of knowing that provides a pragmatic approach to questions about reality, truth, and human understanding. Radical constructivism draws heavily on Jean ...
  • Mullen, Benjamin (School of Architecture, University of Limerick, 2013)
    I would like to offer a brief introduction to this thesis document. The work that follows takes as its staring point the universal theme of love as it could (or should) relate to architecture, historically and presently. ...
  • Olusoji, Olugbenga. J.; Kam, Wern; O'Keeffe, Sinéad (SPIE: The International Society for Optics and Phontonics, 2020)
    The complexity of treating cancerous cells in patients using radiotherapy, requires precision in terms of the total dose received by the patient. The use of scintillating materials at the tip of the fibre for real time ...
  • Zaidi, Muhaned Ali Hussein; Grout, Ian; A'ain, Abu Khari (I.J.S.E.I, 2018)
    This paper considers and presents the design of a rail-to-rail input and output CMOS (complementary metal oxide semiconductor) two-stage operational amplifier (op-amp). The design uses two capacitance based compensation ...
  • O'Connell, Tina; O'Halloran, Maeve; Doody, Owen (Sage Publications Ltd.,, 2013)
    Intellectual disability services recognise people with intellectual disability as a family member and aim to provide effective support that facilitates family cohesion. However, the needs of families and individuals ...
  • Coffey, Gerard (2005)
    The practical effect of the common law principle against double jeopardy is the proscription against retrials for the same criminal offence following an acquittal or conviction.2 Pleading double jeopardy3 is not to be ...
  • Costello, Rory (Taylor and Francis, 2020)
    When national interests are threatened by an international political crisis, there is often a ‘rally around the flag’ effect among both the public and the political elite, interpreted as a patriotic response to an external ...
  • Beattie, James R.; Cummins, Niamh M.; Caraher, Clare; O'Driscoll, Olive M.; Bansal, Aruna T.; Eastell, Richard; Ralston, Stuart H.; Stone, Michael D.; Pearson, Gill; Towler, M.R. (Libertas Academica, 2016)
    Raman spectroscopy was applied to nail clippings from 633 postmenopausal British and Irish women, from six clinical sites, of whom 42% had experienced a fragility fracture. The objective was to build a prediction algorithm ...
  • Cummins, Niamh M.; Day, J.C.C.; Wren, A.W.; Carroll, P.; Murphy, N.; Jakeman, Philip M.; Towler, M.R. (Hindawi Publishing Corporation, 2010)
    Raman data from human fingernails has been analysed to determine if a relationship exists between spectral features and bone quality. Previous work demonstrated a relationship between the manually determined intensity of ...
  • Caraher, Clare; Sophocleous, Antonia; Beattie, Renwick J.; O'Driscoll, Olive M.; Cummins, Niamh M.; Brennan, Orlaith; O'Brien, Fergal J.; Ralston, Stuart H.; Bell, Steven E.J.; Towler, M.R.; Idris, Aymen I. (Elsevier, 2018)
    Osteoporosis is a common disease characterised by reduced bone mass and an increased risk of fragility fractures. Low bone mineral density is known to significantly increase the risk of osteoporotic fractures, however, the ...
  • Egan, Patrick; Connelly, Michael J.; Lakestani, Fereydoun; Whelan, Maurice P. (Optical Society of America, 2006)
    With analog scanning, time-domain low-coherence interferometry lacks precise depth information, and optical carrier generation demands a linear scanning speed. Full-field heterodyne low-coherence interferometry that uses ...
  • Hayes, Sara; Kacper Uszynski, Marcin; Motl, Robert W.; Gallagher, Stephen; Larkin, Aidan; Newell, John; Scarrott, Carl; Coote, Susan (BMJ Publishing Group, 2017)
    Objective To investigate feasibility of multiple sclerosis (MS) exercise guidelines for inactive people with MS (PwMS) and to examine preliminary efficacy for walking. To investigate effect of augmenting that intervention ...