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The role of fat in gastric emptying and satiety : acute and chronic effects

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dc.contributor.author Shafat, Amir
dc.contributor.author Clegg, Miriam E.
dc.date.accessioned 2011-04-08T15:32:40Z
dc.date.available 2011-04-08T15:32:40Z
dc.date.issued 2009
dc.identifier.uri http://hdl.handle.net/10344/998
dc.description peer-reviewed en_US
dc.description.abstract Dietary fat is an important factor in the aetiology of obesity and the metabolic syndrome. It has been widely debated whether gastric emptying (GE) is altered in obesity. GE times have been reported as both longer and shorter in obese individuals compared with matched lean individuals. However, the general consensus is that GE is accelerated and satiety is lower in obesity. Research has implicated a high-fat (HF) diet in these findings. A single HF meal has a longer GE time than a low-fat meal and can even delay GE of the subsequent meal. However, an HF diet has shown different effects. Feeding a HF diet adapts gastrointestinal function to reduce GE times in comparison with a low-fat diet. Increased GE may lead to decreased satiety and faster onset of subsequent eating episodes. Further results have suggested that consuming an HF diet for 14 d increases the GE rate of HF food but not low-fat food. Consuming HF diets for 2 weeks has also been shown to increase food intake. Decreased satiation following an HF diet may cause increased food intake and a positive energy balance, potentially resulting in a gradual increase in adiposity. Recent results have suggested that gastrointestinal transit is accelerated following only 3 d on a HF diet. The variable GE times reported in obesity may be associated with interactions between the HF diet and obesity and not simply the obese state. en_US
dc.language.iso eng en_US
dc.publisher Nutrition Society en_US
dc.relation.ispartofseries Proceedings of the Nutrition Society, Postgraduate Symposium on ‘Multidisciplinary approaches to nutritional problems’, University of Nottingham, 30 June–3 July 2008;
dc.relation.uri http://dx.doi.org/10.1017/S0029665108008859
dc.subject diet en_US
dc.subject fat en_US
dc.subject gastric emptying en_US
dc.subject satiety en_US
dc.title The role of fat in gastric emptying and satiety : acute and chronic effects en_US
dc.type Conference item en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.type.restriction none en
dc.contributor.sponsor IRCSET

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