BID, a pro-apoptotic Bcl-2 family member, promotes cytochrome c release during apoptosis initiated
by CD95L or TNF. Activation of caspase-8 in the latter pathways results in cleavage of BID,
translocation of activated ...
Tumour necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) is a member of the TNF family of cytokines that promotes apoptosis and NF-kB activation. Here we show that recombinant hu-TRAIL initiates the activation ...