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The analysis of lactate-pyruvate levels and growth proliferation rates of endothelial cells on urinary bladder matrix: a potential vascular graft

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dc.contributor.author Callanan, Anthony
dc.contributor.author Guihen, Elizabeth
dc.contributor.author Walsh, Michael T.
dc.contributor.author O'Connor, William T.
dc.contributor.author McGloughlin, Timothy M.
dc.date.accessioned 2012-05-24T14:25:40Z
dc.date.available 2012-05-24T14:25:40Z
dc.date.issued 2010
dc.identifier.citation Callanan,Anthony (2010) "The analysis of lactate-pyruvate levels and growth proliferation rates of endothelial cells on urinary bladder matrix: a potential vascular graft,"in Tissue Engineering and Regenerative Medicine International Society – EU Meeting -2010 en_US
dc.identifier.uri http://hdl.handle.net/10344/2215
dc.description peer-reviewed en_US
dc.description.abstract Arterial diseases are a common cause of death in the western world. The development of arterial substitute materials for the improved treatment of cardiovascular diseases is vital. One such material is urinary bladder matrix (UBM) an extracellular matrix material derived from porcine urinary bladder. Studies have reported that UBM contains a highly important factor for vessel and endothelium formation, an intact basement membrane (1). Cellular performance and growth are also important characteristics of an arterial substitute. Lactate is a respiratory metabolite which under optimal aerobic conditions is converted to pyruvate and can be used to measure cellular performance of cells. Thus the lactate/pyruvate (L/P) ratio indicates the respiratory status of a cell (2). The main aim of this research is the investigation of the (L/P) ratios and proliferation rates of human endothelial cells on UBM, to demonstrate its suitability for vascular applications. en_US
dc.language.iso eng en_US
dc.relation.ispartofseries Tissue Engineering and Regenerative Medicine International Society – EU Meeting -2010;
dc.subject lactate-pyruvate levels en_US
dc.subject arterial disease en_US
dc.subject cardiovascular en_US
dc.title The analysis of lactate-pyruvate levels and growth proliferation rates of endothelial cells on urinary bladder matrix: a potential vascular graft en_US
dc.type info:eu-repo/semantics/conferenceObject en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.contributor.sponsor EI en_US
dc.relation.projectid TD 05/121 en_US
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US
dc.internal.authorcontactother Anthony.Callanan@ul.ie


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