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Mathematics & Statistics

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Recent Submissions

  • Cribbin, Laura B (University of Limerick, 2013)
    Under the influence of regional groundwater ow, pollution in an aquifer can migrate to streams or wells. This can have catastrophic consequences for human health and local ecosystems. Fortunately, there is a suite of ...
  • Murphy, Ellen (University of Limerick, 2014)
    Applied mathematicians have long sourced problems from industrial processes. The relationship between mathematics and industry is mutually beneficial. Mathematical models provide industry with invaluable insights into ...
  • Stembalska, Agnieszka; Leszczyński, Przemysław; Gil, Justyna; Ramsey, David; Pitala, Grzegorz; Maciejczyk, Adam; Frączek, Marcin (Wiley, 2014)
    Laryngeal squamous cell carcinoma (LSCC) belongs to the heterogeneous group of head and neck cancers. In the etiology of LSCC, beside important environmental factors, genetic and epigenetic factors play a role in defining ...
  • Ramsey, David (Elsevier, 2012)
    A model of partnership formation based on two traits, called beauty and character, is presented. There are two classes of individual and partners must be of di erent classes. Individuals prefer prospective partners with ...
  • Ramsey, David; Futschik, Andreas (Internaitonal Statistical Institute, 2011)
    An important problem in genetics is detecting single nucleotide polymorphisms (SNPs), sites along the genome at which a population shows variation. The focus is on the detection of rare variants. Pooling individuals ...
  • Alpern, S; Katrantzi, I; Ramsey, David (Elsevier, 2013)
    We analyze a model of partnership formation in which players’ preferences are based on the age of a prospective partner. There are two classes of individuals, called for convenience here male and female. Males and females ...
  • Karpinski, Pawel; Myszka, Aleksander; Ramsey, David; Misiak, Blazej; Gil, Justyna; Laczmanska, Izabela; Grzebieniak, Zygmunt; Sebzda, Tadeusz; Smigiel, Robert; Stembalska, Agnieszka; Sasiadek, Maria Malgorzata (Elsevier, 2010)
    The CpG island methylator phenotype (CIMP), together with extensive promoter methylation, is regarded as one of the mechanisms involved in colorectal carcinogenesis (CRC). The mechanisms underlying the presence of CIMP in ...
  • Karpinski, Pawel; Szmida, Elzbieta; Misiak, Blazej; Ramsey, David; Leszczynski, Przemyslaw; Bebenek, Marek; Sedziak, Tomasz; Grzebieniak, Zygmunt; Jonkisz, Anna; Lebioda, Arleta; Sasiadek, Maria Malgorzata (Wiley, 2012)
    Background: Recent investigations have demonstrated the clear heterogeneity of sporadic colorectal cancer (CRC) with regard to CpG island methylation. Two unsupervised cluster analyses revealed that CRCs form three distinct ...
  • Laczmanska, Izabela; Karpinski, Pawel; Bebenek, Marek; Sedziak, Tomasz; Ramsey, David; Szmida, Elżbieta; Sasiadek, Maria Malgorzata (Nature Publishing Group, 2013)
    Introduction: The activity of phosphatases could be influenced by genetic, as well as epigenetic alterations. In our study we have investigated the methylation status of four PTPRs: PTPRM, PTPRT, PTPRR and PTPRZ1, which ...
  • Ramsey, David; Futschik, Andreas (IWSM, 2011)
    We consider the optimal pooling of DNA to detect single nucleotide polymorphisms (SNPs), sites along the genome at which a population shows variation. The focus is on the detection of low frequency variants. Pooling ...
  • Sheikhi, Ali; Ramsey, David (Irish Statistical Association, 2012)
    Genome sequencing includes methods and technologies that are used for determining the order of nucleotides (A, T, C or G) along a DNA sequence. A single nucleotide polymorphism or SNP is a DNA sequence variation occurring ...
  • Sheikhi, Ali; Janghorbani, Mohsen; Soleimani, Bahram (Irish Statistical Association, 2010)
    no abstract available
  • Sheikhi, Ali; Ramsey, David (IWSM, 2012)
    A single nucleotide polymorphism or SNP is a site of the genome where variation occurs within a population. Almost all SNPs have only two alleles (variants). In this work, we consider a statistical method based on a ...
  • Burke, Kevin; MacKenzie, Gilbert (IWSM, 2013)
    The proportional hazards (PH) assumption in survival analysis may not always be appropriate. If data do not obey the assumption then we will reach incorrect conclusions by making it. For example we may find a covariate to ...
  • Donnelly, David W; Hegarty, Avril; Sharp, Linda; Carsin, Anne-Elie; Deady, Sandra; McCluskey, Neil; Comber, Harry; Gavin, Anna (Hindawi Publishing Corporation, 2013)
    Background. Cancer incidence rates vary considerably between countries and by socioeconomic status (SES). We investigate the impact of SES upon the relative cancer risk in two neighbouring countries. Methods. Data on ...
  • Shiely, Frances; Perry, Ivan J; Lutomski, Jennifer; Harrington, Janas; Kelliher, Cecily C; McGee, Hannah; Hayes, Kevin (BioMed Central, 2010)
    Background: As the use of self-reported data to classify obesity continues, the temporal change in the accuracy of self-report measurement when compared to clinical measurement remains unclear. The objective of this study ...
  • Lynch, Joseph (University of Limerick, 2011)
    In the survival analysis literature, the standard model for data analysis is the semi-parametric Proportional Hazard (PH) model of Cox (1972). MacKenzie (1996) introduced the Generalised Time Dependent Logistic (GTDL) ...
  • Nolan, Clifford J.; Cheney, Margaret; Dowling, Thomas; Gaburro, Romina (Institute of Physics Publishing, 2006)
    Multiply scattered waves are often neglected in imaging methods; largely because of the inability of popular algorithms to deal with the associated nonlinear models. This paper shows that by incorporating a known environment ...
  • Bandeira, Afonso; Bell, Christopher G.; Charpin, Jean P. F.; Gaburro, Romina; Soussi, Sofiane; Wilson, Eddie R. (2009)
    The design of solar panels is investigated. Different aspects of this problem are presented. A formula averaging the solar energy received on a given location is derived first. The energy received by the collecting solar ...
  • Gaburro, Romina; Lionheart, William R. B. (2010)
    The problem in Optical Tomography of determining the spacially dependent absorption coefficient in an anisotropic medium with a-priori known strong scattering is considered. The problem is modelled by the diffusion ...

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